Product Name: Trelagliptin
CAS No.: 865759-25-7
Information: DPP-4 inhibitor,long-acting and selective.
Description: Trelagliptin is a long acting inhibitor of dipeptidyl peptidase-4 (DPP-4).
Other Names: SYR-472, SYR472, SYR 472, Trelagliptin,
Chemical Name: 2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]-4-fluorobenzonitrile
Canonical SMILES: CN1C(=O)C=C(N(C1=O)CC2=C(C=CC(=C2)F)C#N)N3CCCC(C3)N
MF: C18H20FN5O2
MW: 357.3821
Purity: 99%
Type: Antidiabetic Agents
Grade Standard: Medicine Grade
Model Number: API-Trelagliptin
Solubility: Soluble in DMSO > 10 mM
Storage: Store at -20°C
Brand Name: Huavet
Place of Origin: Shaanxi, China (Mainland)
General tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition: Evaluation sample solution: ship with blue ice. All other available size: ship with RT , or blue ice upon request
Background: Trelagliptin is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). Two Phase II clinical studies have been completed with Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus. Phase III clinical studies with trelagliptin in Japan to evaluate its safety and efficacy in a once-weekly oral treatment regimen. Currently, all available DPP-4 inhibitors are dosed once-daily. A once-weekly treatment, such as trelagliptin, would provide patients with a convenient treatment alternative and has the potential to improve treatment compliance.
Usage: Pharmaceutical Intermediates
Inventory status: in stock
Shelf life: 2 years
Sample: Available
COA (Certificate of Analysis): Available
MSDS (Material Safety Data Sheet): Available
HPLC Spectrum: Available
ISO: Approved
GC: Available
NMR (Nuclear Magnetic Resonance): Available
Packaging Details: 1g, 5g, 10g, 50g, 100g/bottle, 1kg/tin for trial order,25kg/drum for commercial quantity. Specific packing required by customer
Delivery Detail: Prompt shipment
Related Antibodies:
*DPP4 Antibody (89F4)
*DPP4 Antibody (68R3)
*DPP4 Antibody (46I2)
*DPP4 Antibody
