Product Description

Product Name: Aripiprazole

CAS No.:129722-12-9

Information: Antipsychotic

Chemical Name 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one

Other Names: ABILIFY; ABILITAT; ARIPIPRAZOLE; ARIPIPRAZOLE-D8; OPC 14597; OPC 31;

7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone; OPC-14597, OPC-31,; 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one; Arpiprazole; Alipiprazole; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydro-2(1H)-quinolinone; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydrocarbostyril; Abilify-d8; Abilitat-d8; OPC 14597-d8; OPC 31-d8-

Canonical SMILES: C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl

MF: C23H27Cl2N3O2

MW: 448.39

Solubility: Soluble in DMSO > 10 mM 

Storage: Store at -20°C 

General tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. 

Shipping Condition: Evaluation sample solution: ship with blue ice. All other available size: ship with RT , or blue ice upon request

Background: Aripiprazole is a novel and atypical antipsychotic [1].

Aripiprazole has been found to be a dopamine-serotonin system stabilizer with potent partial agonist activity at dopamine D2 and 5-HT1A receptors and antagonist activity at 5-HT2A receptors. In addition, aripiprazole has been reported to label with the agonist [125I]7-OH-PIPAT and with the antagonist [3H]spiperone with 0.34±0.02nM and 0.70±0.22nM, respectively. Besides, aripiprazole has been revealed to dose-dependently and potently inhibit the increase in cAMP accumulation stimulated by forskolin in CHO cells and HEK-293 cells. Other results have also been reported that aripiprazole completely inhibited the increase GTPase activity stimulated by the D2 receptor agonist quinpirole in rat striatal membranes [1].

Purity: 99.0%min

Appearance: Off-white or white crystal

Assay: 99.0%min

Melting Point:136-142℃

Chloride:≤0.02%

Sulphated Ash:≤0.1%

Heavy Type: Central Nervous System Agents

Grade Standard: Medicine Grade

Metals:≤10ppm

Model Number: API-Aripiprazole

Brand Name: Huavet

Place of Origin: Shaanxi, China (Mainland)

Usage: Pharmaceutical Intermediates

Inventory status: in stock

Shelf life: 2 years

Sample: Available

COA (Certificate Of Analysis): Available

MSDS (Material Safety Data Sheet): Available

HPLC Spectrum: Available

ISO: Approved

GC: Available

NMR (Nuclear Magnetic Resonance): Available

Packaging Details: 1g,5g,10g,50g,100g/bottle, 1kg/tin for trial order,25kg/drum for commercial quantity. Specific packing required by customer

Delivery Detail: Prompt shipment