Chemical name:
Tilmicosin(IUPAC): (10E,12E)-(3R,4S,5S,6R,8R,14R,15R)-14-(6-deoxy-2,3-di-O-methyl-b-d-allo-hexopyranosyoxymethyl)-5-(3,6-dideoxy-3-dimethylamino-b-d-gluco-hexapyranosyloxy)-6-[2-(cis-3,5-dimethyl-piperidino)ethyl]-3-hydroxy-4,8,12-trimethyl-9-oxoheptadeca-10,12-dien-15-olide
Chemical Abstracts Services Name: tylosin,4A-O-de(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-20-deoxy-20-(3,5-dimethyl-1-piperidinyl)-(20(cis: trans))
C.A.S. number: 108050-54-0
Synonyms: 20-Deoxy-20-(3,5-dimethylpiperidin-1-yl)-desmycosin
Structural formula
Molecular formula: C46H80N2O13
Molecular weight: 869.15
Melting point: Not determined
Standard:USP27
Description:
A white or off-white powder, Freely soluble (1500 mg/L or greater) in organic solvents (hexane,acetone, acetonitrile, chloroform, dichloromethane, ethyl acetate, methanol, tetrahydrofuran); water solubility is temperature and pH dependent, but is 566 mg/mL at pH 7 and 25°C.
Purity:
Tilmicosin consists of 82-88% cis isomer and 12-18% trans isomer, as determined by liquid chromatographic assay.(85%MIN)
Indications:
Tilmicosin is a macrolide antibiotic synthesized from tylosin,It developed for veterinary use only.and it has an antibacterial spectrum similar to tylosin with enhanced activity against Pasteurella haemolytica, P. multocida, Actinobacillus pleuropneumoniae, mycoplasma species and other microorganisms found sensitive to this compound. It is recommended for treatment and prevention of pneumonia in cattle, sheep,poultry and pigs, Not show resistance and cross-resistance with other antibiotic often used in clinic. Mainly used in the Pleuropneumonia and the infection caused by Pasteurellaceae , Pasteurella and mycoplasma
Packing:15kg Per Fibre drug
Storage:Protected from light , stored hermetically and in a dry place.
Shelf Life:Three years |
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